| Laura and John Arnold Foundation | Houston | 6794 | $2.1B | $308K |
| Michael & Susan Dell Foundation | Austin | 8703 | $1.5B | $173K |
| Musk Foundation | Austin | 254 | $1.4B | $5.7M |
| Je and Le Mabee Foundation Inc | Midland | 1349 | $1.0B | $767K |
| Houston Endowment Inc | Houston | 4665 | $981.5M | $210K |
| The Moody Foundation | Galveston | 2713 | $869.8M | $321K |
| The Brown Foundation Inc | Houston | 6300 | $818.7M | $130K |
| Art Bridges Inc | Fort Worth | 4 | $557.4M | $139.3M |
| The Rees-Jones Foundation | Dallas | 1718 | $546.8M | $318K |
| Kinder Foundation | Houston | 764 | $533.7M | $699K |
| Bhp Foundation | Houston | 354 | $520.7M | $1.5M |
| The Robert a Welch Foundation | Houston | 691 | $392.4M | $568K |
| Rainwater Charitable Foundation | Fort Worth | 2775 | $389.9M | $141K |
| Ting Tsung & Wei Fong Chao Foundation | Houston | 1952 | $336.8M | $173K |
| O'Donnell Foundation | Dallas | 63 | $307.9M | $4.9M |
| Dan L Duncan Foundation | Houston | 490 | $304.5M | $621K |
| Exxonmobil Foundation | The Woodlands | 670 | $286.9M | $428K |
| Amon G Carter Foundation | Fort Worth | 178 | $281.0M | $1.6M |
| The T Boone Pickens Foundation | Dallas | 18 | $268.6M | $14.9M |
| Ed Rachal Foundation | Corpus Christi | 1051 | $259.0M | $246K |
| The Eugene Mcdermott Foundation | Dallas | 985 | $254.2M | $258K |
| Texas Instruments Foundation | Dallas | 37658 | $239.9M | $6K |
| Shell Oil Company Foundation | Houston | 74030 | $239.8M | $3K |
| The Terry Foundation | Houston | 164 | $239.7M | $1.5M |
| Burnett Foundation | Fort Worth | 92 | $238.8M | $2.6M |
| Scharbauer Foundation Inc | Midland | 830 | $234.9M | $283K |
| Tll Temple Foundation | Lufkin | 11 | $220.8M | $20.1M |
| Meadows Foundation Inc | Dallas | 1456 | $218.2M | $150K |
| Sid W Richardson Foundation | Fort Worth | 9 | $202.9M | $22.5M |
| Knobloch Family Foundation | Houston | 398 | $199.0M | $500K |
| The Gordon & Mary Cain Foundation | Houston | 13 | $195.7M | $15.1M |
| Impetus Foundation | San Antonio | 406 | $193.9M | $478K |
| George Foundation | Richmond | 418 | $190.3M | $455K |
| Leducq Foundation | Houston | 849 | $184.7M | $218K |
| Dian Graves Owen Foundation | Abilene | 1590 | $181.3M | $114K |
| F M H Foundation | Midland | 694 | $171.5M | $247K |
| The Powell Foundation | Houston | 1886 | $168.8M | $89K |
| The Cullen Foundation | Houston | 248 | $164.6M | $664K |
| Albert & Bessie Mae Kronkosky Charitable | Dallas | 10 | $159.0M | $15.9M |
| Hildebrand Foundation | Houston | 1095 | $158.3M | $145K |
| Stanley E Fulton Family Foundation | Dallas | 201 | $156.6M | $779K |
| The Mulva Family Foundation | Austin | 208 | $156.2M | $751K |
| Valley Baptist Legacy Foundation | Harlingen | 468 | $155.8M | $333K |
| The Wildcat Foundation | Fort Worth | 376 | $154.3M | $410K |
| The William Stamps Farish Fund | Houston | 1284 | $154.2M | $120K |
| The Henderson-Wessendorff Foundation | Richmond | 1382 | $154.0M | $111K |
| The Wortham Foundation Inc | Houston | 32 | $151.4M | $4.7M |
| Ainslie Foundation | Dallas | 916 | $148.2M | $162K |
| Hamill Foundation | Houston | 983 | $145.1M | $148K |
| The Jay Pritzker Foundation | Houston | 300 | $143.4M | $478K |
| The Elkins Foundation | Houston | 967 | $143.3M | $148K |
| The Karakin Foundation | Abilene | 1074 | $143.0M | $133K |
| Mays Family Foundation | San Antonio | 177 | $138.8M | $784K |
| Ch Foundation Inc | Lubbock | 870 | $135.1M | $155K |
| Centerpoint Energy Foundation Inc | Houston | 3189 | $132.7M | $42K |
| Heavenly Fathers Foundation | Cisco | 14 | $129.9M | $9.3M |
| David Weekley Family Foundation | Houston | 967 | $127.5M | $132K |
| The Fondren Foundation | Houston | 11 | $126.6M | $11.5M |
| John P Mcgovern Foundation | Houston | 2775 | $125.6M | $45K |
| Robert J & Helen C Kleberg Foundation | San Antonio | 393 | $122.6M | $312K |
| Helen Jones Foundation Inc | Lubbock | 434 | $118.3M | $273K |
| Albert & Margaret Alkek Foundation | Houston | 452 | $115.0M | $254K |
| The John M O'Quinn Foundation | Houston | 803 | $113.7M | $142K |
| The Morris Foundation | Fort Worth | 690 | $113.6M | $165K |
| The Robert and Janice Mcnair Foundation | Houston | 764 | $113.2M | $148K |
| At&T Foundation | Dallas | 4145 | $112.3M | $27K |
| The Priddy Foundation | Wichita Falls | 1215 | $110.6M | $91K |
| Eula Mae and John Baugh Foundation | Jersey Village | 319 | $109.5M | $343K |
| The Cynthia & George Mitchell Foundation | The Woodlands | 3151 | $107.6M | $34K |
| Mary K and Clifford Grum Foundation | Lufkin | 121 | $105.1M | $869K |
| Kickapoo Springs Foundation | Abilene | 1211 | $104.4M | $86K |
| The Lanier Theological Library Foundation | Houston | 198 | $104.0M | $525K |
| Hoblitzelle Foundation | Dallas | 1058 | $101.7M | $96K |
| Simon Bolivar Foundation Inc | Houston | 424 | $101.1M | $238K |
| The Ewing Halsell Foundation | San Antonio | 561 | $100.1M | $178K |
| The Hunt Family Foundation | El Paso | 1496 | $99.8M | $67K |
| Still Water Foundation II | Austin | 692 | $99.5M | $144K |
| Hillcrest Foundation | Dallas | 1304 | $98.8M | $76K |
| Santander Consumer Usa Inc Foundation | Dallas | 465 | $98.6M | $212K |
| Musk Foundation | Austin | 33 | $98.4M | $3.0M |
| The Legett Foundation | Abilene | 1249 | $97.5M | $78K |
| Stoller Foundation | Houston | 1100 | $96.2M | $87K |
| The Addy Foundation | Dallas | 606 | $95.1M | $157K |
| Jerold B Katz Foundation | Houston | 84 | $91.1M | $1.1M |
| Crow Family Foundation Inc | Dallas | 2 | $90.1M | $45.0M |
| The Sarah and Ross Perot Jr Foundation | Dallas | 479 | $90.0M | $188K |
| Swalm Foundation | Wellington | 11 | $89.9M | $8.2M |
| Harry Bass Foundation | Dallas | 511 | $89.3M | $175K |
| Abell-Hanger Foundation | Midland | 3075 | $88.8M | $29K |
| Mckesson Foundation Inc | Dallas | 8357 | $88.4M | $11K |
| Wayne Duddlesten Foundation | Houston | 544 | $87.7M | $161K |
| Bnsf Railway Foundation | Fort Worth | 15297 | $87.3M | $6K |
| Hamon Charitable Foundation | Dallas | 341 | $85.8M | $251K |
| The Klesse Foundation | San Antonio | 13 | $85.3M | $6.6M |
| Huffington Foundation | Houston | 355 | $84.6M | $238K |
| Toyota Usa Foundation | Plano | 274 | $84.1M | $307K |
| The Usaa Foundation Inc | San Antonio | 9 | $84.1M | $9.3M |
| The Nasher Foundation | Forney | 13 | $84.1M | $6.5M |
| Greater Texas Foundation | Bryan | 865 | $83.7M | $97K |
| The Sheth Sangreal Foundation | Austin | 118 | $83.4M | $707K |