| Bill & Melinda Gates Foundation | Seattle | 48097 | $65.7B | $1.4M |
| Bill & Melinda Gates Foundation Trust | Seattle | 14 | $60.7B | $4.3B |
| Merck Patient Assistance Program Inc | Kenilworth | 10 | $17.2B | $1.7B |
| The Susan Thompson Buffett Foundation | Omaha | 5539 | $8.8B | $1.6M |
| The Bloomberg Family Foundation Inc | New York | 2459 | $8.0B | $3.3M |
| The Ford Foundation | New York | 35305 | $7.9B | $224K |
| Glaxosmithkline Patient Access | Philadelphia | 9 | $6.9B | $771.3M |
| The Robert Wood Johnson Foundation | Princeton | 42184 | $6.6B | $156K |
| Foundation to Promote Open Society | New York | 11460 | $6.5B | $566K |
| Wk Kellogg Foundation Trust - No 5315 | Battle Creek | 15 | $6.3B | $419.4M |
| The William & Flora Hewlett Foundation | Menlo Park | 19320 | $5.7B | $296K |
| Wk Kellogg Foundation | Battle Creek | 27159 | $5.1B | $190K |
| Gordon E and Betty I Moore Foundation | Palo Alto | 14528 | $4.7B | $323K |
| Walton Family Foundation Inc | Bentonville | 9454 | $4.5B | $481K |
| John D and Catherine T Macarthur Foundation (Consolidated) | Chicago | 18680 | $4.2B | $224K |
| The Jpb Foundation | New York | 4811 | $4.0B | $837K |
| Volkswagenstiftung | Salt Lake City | 8 | $3.6B | $452.6M |
| The Bank of America Charitable | Charlotte | 590128 | $3.6B | $6K |
| Wellspring Philanthropic Fund Inc | New York | 10883 | $3.3B | $305K |
| The Leona M and Harry B Helmsley | New York | 5036 | $3.3B | $653K |
| Sergey Brin Family Foundation | San Francisco | 1166 | $3.2B | $2.7M |
| Charles and Lynn Schusterman Family Foundation | Tulsa | 9 | $3.2B | $353.5M |
| The David and Lucile Packard Foundation | Los Altos | 9244 | $3.1B | $335K |
| The Sherwood Foundation | Omaha | 7970 | $3.1B | $387K |
| Otsuka Patient Assistance Foundation Inc | Princeton | 14 | $3.1B | $220.3M |
| The California Endowment | Los Angeles | 24900 | $3.1B | $123K |
| Howard G Buffett Foundation | Decatur | 547 | $3.0B | $5.5M |
| The Simons Foundation Inc | New York | 13121 | $2.8B | $210K |
| Good Ventures Foundation | Palo Alto | 2850 | $2.6B | $929K |
| Conrad N Hilton Foundation | Agoura Hills | 9960 | $2.4B | $240K |
| Nsn Foundation Inc | Roseland | 24 | $2.2B | $93.4M |
| Novo Foundation | Brooklyn | 6322 | $2.2B | $353K |
| Chan Zuckerberg Initiative Foundation | Palo Alto | 829 | $2.2B | $2.7M |
| Wells Fargo Foundation | Minneapolis | 9 | $2.1B | $237.0M |
| Laura and John Arnold Foundation | Houston | 6794 | $2.1B | $308K |
| The Carl Victor Page Memorial Foundation | Palo Alto | 78 | $2.0B | $25.0M |
| Open Society Institute | New York | 7327 | $1.7B | $231K |
| The Kresge Foundation | Troy | 8441 | $1.6B | $192K |
| Mother Cabrini Health Foundation Inc | New York | 6289 | $1.6B | $257K |
| Charles Stewart Mott Foundation | Flint | 10100 | $1.6B | $157K |
| Windgate Charitable Foundation Inc | Little Rock | 1621 | $1.5B | $948K |
| The Mcknight Foundation | Minneapolis | 10489 | $1.5B | $146K |
| Robert W Woodruff Foundation Inc | Atlanta | 292 | $1.5B | $5.2M |
| Miramar Charitable Foundation | Ft Mitchell | 1756 | $1.5B | $861K |
| Michael & Susan Dell Foundation | Austin | 8703 | $1.5B | $173K |
| The Harry and Jeanette Weinberg | Owings Mills | 8388 | $1.5B | $179K |
| John Templeton Foundation | West Conshohocken | 5158 | $1.5B | $287K |
| Crankstart Foundation | San Francisco | 3117 | $1.5B | $470K |
| Wyss Foundation | Washington | 9 | $1.5B | $161.6M |
| Musk Foundation | Austin | 254 | $1.4B | $5.7M |
| Waverley Street Foundation | Palo Alto | 565 | $1.4B | $2.6M |
| Knight Foundation | Beaverton | 64 | $1.4B | $21.2M |
| The James Irvine Foundation | San Francisco | 5478 | $1.3B | $246K |
| Margaret a Cargill Foundation | Eden Prairie | 3031 | $1.3B | $433K |
| S&G Foundation Inc | Albany | 26 | $1.3B | $50.4M |
| Sequoia Climate Foundation | Irvine | 857 | $1.3B | $1.5M |
| The Benificus Foundation | San Carlos | 431 | $1.2B | $2.9M |
| Richard King Mellon Foundation | Pittsburgh | 3268 | $1.2B | $377K |
| Shelby Cullom Davis Charitable Fund Inc | Wilmington | 1052 | $1.2B | $1.2M |
| The Ralph C Wilson Jr Foundation | Detroit | 4535 | $1.2B | $268K |
| Wal-Mart Foundation | Bentonville | 3314 | $1.2B | $359K |
| The Heising-Simons Foundation | Los Altos | 5376 | $1.2B | $218K |
| The Arthur M Blank Family Foundation | Atlanta | 4534 | $1.2B | $255K |
| The Eli and Edythe Broad Foundation | Los Angeles | 1097 | $1.2B | $1.0M |
| Bezos Family Foundation | Seattle | 8 | $1.1B | $136.1M |
| Je and Le Mabee Foundation Inc | Midland | 1349 | $1.0B | $767K |
| The Skoll Foundation | Palo Alto | 2616 | $1.0B | $394K |
| Clark Charitable Foundation Inc | Bethesda | 1564 | $1.0B | $659K |
| Valhalla Foundation | Woodside | 752 | $1.0B | $1.3M |
| The Paul E Singer Foundation | New York | 584 | $996.9M | $1.7M |
| Steven & Alexandra Cohen Foundation Inc | Stamford | 1284 | $985.5M | $767K |
| Robertson Foundation | New York | 2276 | $983.8M | $432K |
| Houston Endowment Inc | Houston | 4665 | $981.5M | $210K |
| Barr Foundation | Boston | 7172 | $952.9M | $133K |
| Doris Duke Charitable Foundation Inc | New York | 3485 | $945.4M | $271K |
| The Eric and Wendy Schmidt Fund for | Palo Alto | 1487 | $928.4M | $624K |
| Annie E Casey Foundation Inc | Baltimore | 14058 | $916.5M | $65K |
| The Moody Foundation | Galveston | 2713 | $869.8M | $321K |
| J E Barbey 8 Fbo Tenacre Fdn | Pittsburgh | 11 | $854.4M | $77.7M |
| The Koum Family Foundation | Menlo Park | 1212 | $846.3M | $698K |
| H&H Evergreen Foundation | Menlo Park | 30 | $838.5M | $27.9M |
| The Brown Foundation Inc | Houston | 6300 | $818.7M | $130K |
| Dogwood Health Trust | Asheville | 5133 | $807.7M | $157K |
| M J Murdock Charitable Trust | Vancouver | 6905 | $807.5M | $117K |
| Jack Joseph & Morton Mandel Foundation | Cleveland | 2264 | $778.3M | $344K |
| The David Tepper Charitable Foundation | Livingston | 1415 | $777.0M | $549K |
| The Heinz Endowments | Pittsburgh | 6313 | $774.3M | $123K |
| Tosa Foundation | Portola Valley | 1362 | $759.4M | $558K |
| Harold Alfond Foundation | Portland | 610 | $753.0M | $1.2M |
| The Donald B and Dorothy L | Harrisburg | 13 | $748.2M | $57.6M |
| Otto Bremer Trust | St Paul | 10380 | $720.6M | $69K |
| Walter Scott Family Foundation | Omaha | 364 | $719.2M | $2.0M |
| Citi Foundation | New York | 1518 | $718.6M | $473K |
| Blavatnik Family Foundation | New York | 1237 | $716.4M | $579K |
| Daniels Fund | Denver | 9772 | $710.0M | $73K |
| The Anschutz Foundation | Denver | 10 | $705.2M | $70.5M |
| Friday Foundation | Medina | 39 | $693.4M | $17.8M |
| The Klarman Family Foundation | Boston | 1928 | $677.3M | $351K |
| The Starr Foundation | New York | 799 | $651.4M | $815K |
| The Prudential Foundation | Newark | 2391 | $642.9M | $269K |
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