| Pfizer Patient Assistance Foundation Inc | New York | 670 | $13.9B | $20.7M |
| The Bloomberg Family Foundation Inc | New York | 2459 | $8.0B | $3.3M |
| The Ford Foundation | New York | 35305 | $7.9B | $224K |
| Foundation to Promote Open Society | New York | 11460 | $6.5B | $566K |
| The Andrew W Mellon Foundation | New York | 6719 | $4.8B | $716K |
| The Jpb Foundation | New York | 4811 | $4.0B | $837K |
| Jpmorgan Chase Foundation | New York | 122579 | $3.5B | $29K |
| Wellspring Philanthropic Fund Inc | New York | 10883 | $3.3B | $305K |
| The Leona M and Harry B Helmsley | New York | 5036 | $3.3B | $653K |
| The Simons Foundation Inc | New York | 13121 | $2.8B | $210K |
| Carnegie Corporation of New York | New York | 8597 | $2.2B | $260K |
| Novo Foundation | Brooklyn | 6322 | $2.2B | $353K |
| The Edna Mcconnell Clark Foundation | New York | 123 | $2.1B | $17.4M |
| The Rockefeller Foundation | New York | 7731 | $2.1B | $275K |
| Open Society Institute | New York | 7327 | $1.7B | $231K |
| Mother Cabrini Health Foundation Inc | New York | 6289 | $1.6B | $257K |
| Druckenmiller Foundation | New York | 641 | $1.3B | $2.1M |
| S&G Foundation Inc | Albany | 26 | $1.3B | $50.4M |
| The Paul E Singer Foundation | New York | 584 | $996.9M | $1.7M |
| Robertson Foundation | New York | 2276 | $983.8M | $432K |
| Anna-Maria and Stephen Kellen Foundation | New York | 2813 | $964.7M | $343K |
| Doris Duke Charitable Foundation Inc | New York | 3485 | $945.4M | $271K |
| Alfred P Sloan Foundation | New York | 4143 | $751.1M | $181K |
| Citi Foundation | New York | 1518 | $718.6M | $473K |
| Blavatnik Family Foundation | New York | 1237 | $716.4M | $579K |
| Mastercard Impact Fund | Purchase | 666 | $672.3M | $1.0M |
| The Starr Foundation | New York | 799 | $651.4M | $815K |
| Stephen a Schwarzman Foundation | New York | 152 | $639.7M | $4.2M |
| Surdna Foundation Inc | New York | 5183 | $629.3M | $121K |
| The Wallace Foundation | New York | 2857 | $603.1M | $211K |
| Bristol-Myers Squibb Foundation Inc | New York | 59003 | $554.6M | $9K |
| Carson Family Charitable Trust | New York | 1417 | $539.7M | $381K |
| Foundation for a Just Society | New York | 3266 | $528.1M | $162K |
| Gray Foundation | Cohoes | 1465 | $501.7M | $342K |
| Rockefeller Brothers Fund Inc | New York | 5328 | $501.6M | $94K |
| Paulson Family Foundation | New York | 500 | $479.5M | $959K |
| Pepsico Foundation Inc | Purchase | 919 | $469.7M | $511K |
| Overdeck Family Foundation Inc | New York | 9 | $468.2M | $52.0M |
| Blavatnik Family Foundation 2020 | New York | 457 | $464.9M | $1.0M |
| Bernard and Anne Spitzer | New York | 1786 | $442.6M | $248K |
| The Henry Luce Foundation Inc | New York | 4508 | $409.0M | $91K |
| M&T Charitable Foundation | Buffalo | 11 | $408.6M | $37.1M |
| The Stanton Foundation | New York | 1489 | $402.7M | $270K |
| William Randolph Hearst Foundation | New York | 2998 | $396.6M | $132K |
| The Goldman Sachs Foundation | New York | 643 | $376.5M | $585K |
| Arnhold Foundation Inc | New York | 2067 | $374.0M | $181K |
| The Peter and Carmen Lucia Buck | New York | 1258 | $367.5M | $292K |
| The Pfizer Foundation Inc | New York | 79317 | $367.2M | $5K |
| Gerard B Lambert Foundation | Harrison | 188 | $366.7M | $2.0M |
| New York Life Foundation | New York | 7070 | $342.0M | $48K |
| Metlife Foundation | New York | 9 | $336.9M | $37.4M |
| The Shubert Foundation Inc | New York | 5506 | $327.3M | $59K |
| The Hollyhock Foundation Inc | New York | 315 | $326.5M | $1.0M |
| Tansy Charitable Foundation | New York | 97 | $316.0M | $3.3M |
| W P Carey Foundation Inc | New York | 1545 | $315.0M | $204K |
| Jerome L Greene Foundation | New York | 476 | $313.3M | $658K |
| Mjs Foundation Inc | New York | 710 | $312.8M | $441K |
| The Howard Gilman Foundation Inc | New York | 5308 | $311.9M | $59K |
| The Thompson Family Foundation Inc | New York | 1069 | $310.1M | $290K |
| Arcus Foundation | New York | 3572 | $298.2M | $83K |
| Donald a Pels Charitable Trust Utd | Harrison | 1639 | $294.2M | $180K |
| The Marianthi Foundation Inc | New York | 38 | $274.8M | $7.2M |
| The Horace W Goldsmith Foundation | New York | 2411 | $274.2M | $114K |
| The Commonwealth Fund | New York | 5160 | $267.4M | $52K |
| Beth and Ravenel Curry Foundation | New York | 1138 | $266.7M | $234K |
| Pinkerton Foundation | New York | 3463 | $263.5M | $76K |
| The Pindaros Foundation Inc | New York | 23 | $257.9M | $11.2M |
| Leon Levy Foundation | New York | 1512 | $249.6M | $165K |
| Park Foundation Inc | Ithaca | 3674 | $244.9M | $67K |
| Mulago Foundation | New York | 1177 | $234.8M | $199K |
| The Blackrock Charitable Foundation | New York | 217 | $234.6M | $1.1M |
| Peter G Peterson Foundation | New York | 716 | $231.8M | $324K |
| The Blackstone Charitable Foundation | New York | 2188 | $231.1M | $106K |
| The Freeman Foundation | New York | 470 | $230.6M | $491K |
| Siegel Family Endowment | New York | 9 | $228.1M | $25.3M |
| Foundation for a Smoke-Free World Inc | New York | 9 | $225.6M | $25.1M |
| American Express Foundation | New York | 75526 | $222.7M | $3K |
| Nick Simons Foundation | New York | 249 | $219.7M | $882K |
| Sue & Edgar Wachenheim Foundation | Purchase | 217 | $219.7M | $1.0M |
| The E&Ss Foundation Inc | New York | 361 | $214.7M | $595K |
| The John a Hartford Foundation Inc | New York | 989 | $210.0M | $212K |
| Moise Y Safra Foundation Inc | New York | 864 | $209.1M | $242K |
| Quadrivium | New York | 214 | $207.7M | $970K |
| The Grace and Mercy Foundation Inc | New York | 671 | $205.8M | $307K |
| The Pershing Square Foundation | New York | 587 | $204.3M | $348K |
| The Hearst Foundation | New York | 1460 | $203.6M | $139K |
| Marty and Dorothy Silverman Foundation | New York | 2737 | $203.0M | $74K |
| The Christina and Robert Dow Foundation | Tuxedo Park | 131 | $199.4M | $1.5M |
| Founders Pledge Inc | New York | 671 | $197.7M | $295K |
| The Moore Charitable Foundation Inc | New York | 9 | $196.6M | $21.8M |
| The Clark Foundation | New York | 795 | $196.0M | $247K |
| Tl Foundation | Suffern | 110 | $194.8M | $1.8M |
| Deerbrook Charitable Trust | New York | 320 | $194.2M | $607K |
| Esl Charitable Foundation | Rochester | 2218 | $190.0M | $86K |
| Vital Projects Fund Inc | New York | 1291 | $186.1M | $144K |
| Coleman Family Ventures | New York | 731 | $180.9M | $248K |
| The Macmillan Family Foundation Inc | New York | 936 | $177.3M | $189K |
| The G Harold & Leila Y Mathers | Rye Brook | 917 | $170.8M | $186K |
| The Jonathan M Tisch Family Foundation | New York | 206 | $170.4M | $827K |
| Fisher Koch Family Foundation | New York | 75 | $166.6M | $2.2M |
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